Day 3 began with Beth Mooney, stranded on 98* overnight, reaching her maiden Test century, becoming the fourth woman and first Australian to score centuries across all formats.
Australia's innings quickly unraveled, losing 5/9 in a collapse, and they were bowled out for 440, securing a 270-run lead.
Darcie Brown struck early, dismissing Maia Bouchier as England's struggles continued. At tea, England were 30/1 after 14 overs.
Heather Knight and Tammy Beaumont steadied the innings briefly, but Ash Gardner broke through, dismissing Knight for 32.
Alana King delivered a double strike, removing Nat Sciver-Brunt (18) and Sophia Dunkley (4), leaving England reeling at 104/4, trailing by 166.
Gardner dismissed Danni Wyatt-Hodge, and King removed a set Beaumont for 47, as England lost 5/30 in quick time.
Australia continued to chip away at the lower order as England tumbled from 100/3 to 148/10, undone by King and Gardner's spin and Brown's raw pace.
Winning the One-Off Test by an innings and 122 runs, Australia whitewashed England 16-0 in the 2025 Women's Ashes series.
Australia's 2025 Ashes Series Results
Annabel Sutherland, who became the first woman to score a Test century at the MCG, was named Player of the Match.
Joint-highest wicket-taker in a single multi-format Ashes series, Alana King was named the Player of the Series.